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Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium

Repurposing existing drugs to inhibit SARS-CoV-2 infection in airway epithelial cells (AECs) is a quick way to find novel treatments for COVID-19. Computational screening has found dicoumarol (DCM), a natural anticoagulant, to be a potential SARS-CoV-2 inhibitor, but its inhibitory effects and possi...

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Detalles Bibliográficos
Autores principales: Peng, Yang, Chen, Shi-ying, Wang, Zhao-ni, Zhou, Zi-qing, Sun, Jing, Zhang, Gui-an, Li, Jia, Wang, Lei, Zhao, Jin-cun, Tang, Xiao Xiao, Wang, De-Yun, Zhong, Nan-shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256976/
https://www.ncbi.nlm.nih.gov/pubmed/37301869
http://dx.doi.org/10.1038/s41392-023-01511-7