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Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium
Repurposing existing drugs to inhibit SARS-CoV-2 infection in airway epithelial cells (AECs) is a quick way to find novel treatments for COVID-19. Computational screening has found dicoumarol (DCM), a natural anticoagulant, to be a potential SARS-CoV-2 inhibitor, but its inhibitory effects and possi...
Autores principales: | Peng, Yang, Chen, Shi-ying, Wang, Zhao-ni, Zhou, Zi-qing, Sun, Jing, Zhang, Gui-an, Li, Jia, Wang, Lei, Zhao, Jin-cun, Tang, Xiao Xiao, Wang, De-Yun, Zhong, Nan-shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256976/ https://www.ncbi.nlm.nih.gov/pubmed/37301869 http://dx.doi.org/10.1038/s41392-023-01511-7 |
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