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SP-8356 (A Verbenone Derivative) Inhibits Proliferation, Suppresses Cell Migration and Invasion and Decreases Tumor Growth of Osteosarcoma: Role of PGC-1α/TFAM and AMPK-Activation

OBJECTIVE: Osteosarcoma (OS) is an uncommon sarcoma with osteoid formation in conjunction with malignant mesenchymal cells on histological examination. SP-8356 has been reported to exhibit anti-cancer properties in human cancers. However the impact of SP-8356 on OS is largely unknown. The metabolic...

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Detalles Bibliográficos
Autores principales: Cui, Wenning, Yang, Dengfeng, Chen, Xiaoyan, Yu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257062/
https://www.ncbi.nlm.nih.gov/pubmed/37300290
http://dx.doi.org/10.22074/CELLJ.2023.557404.1052