Cargando…

Parkinson’s disease in a patient with GBA and LRRK2 covariants after acute hypoxic insult: a case report

BACKGROUND: The glucocerebrosidase (GBA) and leucine-rich repeat kinase 2 (LRRK2) genes are associated with the risk of sporadic Parkinson’s disease (PD). As an environmental factor, hypoxic insults may impair dopamine neurons in the substantia nigra and exacerbate PD symptoms. However, covariants o...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yuting, Wei, Lijian, Wu, Zhuohua, Xu, Pingyi, Mo, Mingshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257258/
https://www.ncbi.nlm.nih.gov/pubmed/37301871
http://dx.doi.org/10.1186/s12883-023-03269-5