Mechanisms of glabridin inhibition of integrin α(IIb)β(3) inside-out signals and NF-κB activation in human platelets

BACKGROUND: Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggregation. Glabridin, a prenylated isoflavonoid found in licori...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Chieh, Jayakumar, Thanasekaran, Sheu, Joen-Rong, Hsia, Chih-Wei, Hsia, Chih-Hsuan, Yen, Ting-Lin, Chang, Chao-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257322/
https://www.ncbi.nlm.nih.gov/pubmed/37301823
http://dx.doi.org/10.1186/s13020-023-00779-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257322/
https://www.ncbi.nlm.nih.gov/pubmed/37301823
http://dx.doi.org/10.1186/s13020-023-00779-9

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