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Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis

BACKGROUND: Autoimmune neuropathies can result in long-term disability and incomplete recovery, despite adequate first-line therapy. Kinesin-5 inhibition was shown to accelerate neurite outgrowth in different preclinical studies. Here, we evaluated the potential neuro-regenerative effects of the sma...

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Detalles Bibliográficos
Autores principales: Kohle, Felix, Ackfeld, Robin, Hommen, Franziska, Klein, Ines, Svačina, Martin K. R., Schneider, Christian, Fink, Gereon R., Barham, Mohammed, Vilchez, David, Lehmann, Helmar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257330/
https://www.ncbi.nlm.nih.gov/pubmed/37296476
http://dx.doi.org/10.1186/s12974-023-02822-w