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Raptor couples mTORC1 and ERK1/2 inhibition by cardamonin with oxidative stress induction in ovarian cancer cells

BACKGROUND: A balance on nutrient supply and redox homeostasis is required for cell survival, and increased antioxidant capacity of cancer cells may lead to chemotherapy failure. OBJECTIVE: To investigate the mechanism of anti-proliferation of cardamonin by inducing oxidative stress in ovarian cance...

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Detalles Bibliográficos
Autores principales: Zhu, Yanting, Wang, Shifeng, Niu, Peiguang, Chen, Huajiao, Zhou, Jintuo, Jiang, Li, Li, Danyun, Shi, Daohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257395/
https://www.ncbi.nlm.nih.gov/pubmed/37304865
http://dx.doi.org/10.7717/peerj.15498