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EML4‐ALK biology and drug resistance in non‐small cell lung cancer: a new phase of discoveries

Anaplastic lymphoma kinase (ALK) can be driven to oncogenic activity by different types of mutational events such as point‐mutations, for example F1174L in neuroblastoma, and gene fusions, for example with echinoderm microtubule‐associated protein‐like 4 (EML4) in non‐small cell lung cancer (NSCLC)....

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Detalles Bibliográficos
Autores principales: Elshatlawy, Mariam, Sampson, Josephina, Clarke, Katy, Bayliss, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257413/
https://www.ncbi.nlm.nih.gov/pubmed/37149843
http://dx.doi.org/10.1002/1878-0261.13446