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Fusion sequencing via terminator‐assisted synthesis (FTAS‐seq) identifies TMPRSS2 fusion partners in prostate cancer

Genetic rearrangements that fuse an androgen‐regulated promoter area with a protein‐coding portion of an originally androgen‐unaffected gene are frequent in prostate cancer, with the fusion between transmembrane serine protease 2 (TMPRSS2) and ETS transcription factor ERG (ERG) (TMPRSS2‐ERG fusion)...

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Detalles Bibliográficos
Autores principales: Drazdauskienė, Ugnė, Kapustina, Žana, Medžiūnė, Justina, Dubovskaja, Varvara, Sabaliauskaitė, Rasa, Jarmalaitė, Sonata, Lubys, Arvydas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257418/
https://www.ncbi.nlm.nih.gov/pubmed/37300660
http://dx.doi.org/10.1002/1878-0261.13428