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Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells

Tetraploidy is a hallmark of cancer cells, and tetraploidy‐selective cell growth suppression is a potential strategy for targeted cancer therapy. However, how tetraploid cells differ from normal diploids in their sensitivity to anti‐proliferative treatments remains largely unknown. In this study, we...

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Detalles Bibliográficos
Autores principales: Yoshizawa, Koya, Matsura, Akira, Shimada, Masaya, Ishida‐Ishihara, Sumire, Sato, Fuyu, Yamamoto, Takahiro, Yaguchi, Kan, Kawamoto, Eiji, Kuroda, Taruho, Matsuo, Kazuya, Tamaoki, Nobuyuki, Sakai, Ryuichi, Shimada, Yasuhito, Mishra, Mithilesh, Uehara, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257419/
https://www.ncbi.nlm.nih.gov/pubmed/36688680
http://dx.doi.org/10.1002/1878-0261.13379