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Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing

Lymph node (LN) metastasis is an important factor in determining the treatment and prognosis of oropharyngeal squamous cell carcinoma (OPSCC). Here, we compared the somatic mutational profiles and clonal evolution of primary and metastatic LNs using multiregion sequencing of human papilloma virus (H...

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Detalles Bibliográficos
Autores principales: Sim, Nam Suk, Shin, Su‐Jin, Park, Inho, Yoon, Sun Och, Koh, Yoon Woo, Kim, Se‐Heon, Park, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257422/
https://www.ncbi.nlm.nih.gov/pubmed/36852664
http://dx.doi.org/10.1002/1878-0261.13407