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Investigating the contribution of hyaluronan to the breast tumour microenvironment using multiparametric MRI and MR elastography

Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase alfa (PEGPH20) enzymatically degrades HA and can enhance drug delivery and treatment response in preclinical tumour models...

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Detalles Bibliográficos
Autores principales: Reeves, Emma L., Li, Jin, Zormpas‐Petridis, Konstantinos, Boult, Jessica K. R., Sullivan, James, Cummings, Craig, Blouw, Barbara, Kang, David, Sinkus, Ralph, Bamber, Jeffrey C., Jamin, Yann, Robinson, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257424/
https://www.ncbi.nlm.nih.gov/pubmed/37081807
http://dx.doi.org/10.1002/1878-0261.13437