Spiroindole-containing compounds bearing phosphonate group of potential M(pro)-SARS-CoV-2 inhibitory properties

Microwave-assisted reaction of 3,5-bis((E)-ylidene)-1-phosphonate-4-piperidones 3a‒g with azomethine ylide (produced through interaction of isatins 4 and sarcosine 5) cycloaddition afforded the corresponding (dispiro[indoline-3,2′-pyrrolidine-3′,3″-piperidin]-1″-yl)phosphonates 6a‒l in excellent yie...

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Detalles Bibliográficos
Autores principales: Bekheit, Mohamed S., Panda, Siva S., Kariuki, Benson M., Mahmoud, Sara H., Mostafa, Ahmed, Girgis, Adel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257517/
https://www.ncbi.nlm.nih.gov/pubmed/37329713
http://dx.doi.org/10.1016/j.ejmech.2023.115563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257517/
https://www.ncbi.nlm.nih.gov/pubmed/37329713
http://dx.doi.org/10.1016/j.ejmech.2023.115563

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