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HDGF promotes gefitinib resistance by activating the PI3K/AKT and MEK/ERK signaling pathways in non-small cell lung cancer

Hepatoma-derived growth factor (HDGF) expression is associated with poor prognosis in non-small cell lung cancer (NSCLC); however, whether HDGF affects gefitinib resistance in NSCLC remains unknown. This study aimed to explore the role of HDGF in gefitinib resistance in NSCLC and to discover the und...

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Detalles Bibliográficos
Autores principales: Han, Shuyan, Tian, Zhihua, Tian, Huifang, Han, Haibo, Zhao, Jun, Jiao, Yanna, Wang, Chunli, Hao, Huifeng, Wang, Shan, Fu, Jialei, Xue, Dong, Sun, Hong, Li, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257651/
https://www.ncbi.nlm.nih.gov/pubmed/37301856
http://dx.doi.org/10.1038/s41420-023-01476-0