SENP2 restrains the generation of pathogenic Th17 cells in mouse models of colitis

The molecular mechanisms contributing to the regulation of Th17-mediated inflammation remain underexplored. We here report a SUMO-specific protease (SENP)2-mediated pathway induced in pathogenic Th17 cells that restricts the pathogenesis of inflammatory colitis. SENP2 regulates the maturation of sma...

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Detalles Bibliográficos
Autores principales: Yang, Tsan-Tzu, Chiang, Ming-Feng, Chang, Che-Chang, Yang, Shii-Yi, Huang, Shih-Wen, Liao, Nan-Shih, Shih, Hsiu-Ming, Hsu, Wei, Lin, Kuo-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257679/
https://www.ncbi.nlm.nih.gov/pubmed/37301920
http://dx.doi.org/10.1038/s42003-023-05009-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257679/
https://www.ncbi.nlm.nih.gov/pubmed/37301920
http://dx.doi.org/10.1038/s42003-023-05009-4

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