Generalized precursor prediction boosts identification rates and accuracy in mass spectrometry based proteomics

Data independent acquisition mass spectrometry (DIA-MS) has recently emerged as an important method for the identification of blood-based biomarkers. However, the large search space required to identify novel biomarkers from the plasma proteome can introduce a high rate of false positives that compr...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Aaron M., Karlsson, Christofer, Mohanty, Tirthankar, Hartman, Erik, Vaara, Suvi T., Linder, Adam, Malmström, Johan, Malmström, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257694/
https://www.ncbi.nlm.nih.gov/pubmed/37301900
http://dx.doi.org/10.1038/s42003-023-04977-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257694/
https://www.ncbi.nlm.nih.gov/pubmed/37301900
http://dx.doi.org/10.1038/s42003-023-04977-x

Ejemplares similares