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Generalized precursor prediction boosts identification rates and accuracy in mass spectrometry based proteomics
Data independent acquisition mass spectrometry (DIA-MS) has recently emerged as an important method for the identification of blood-based biomarkers. However, the large search space required to identify novel biomarkers from the plasma proteome can introduce a high rate of false positives that compr...
Autores principales: | Scott, Aaron M., Karlsson, Christofer, Mohanty, Tirthankar, Hartman, Erik, Vaara, Suvi T., Linder, Adam, Malmström, Johan, Malmström, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257694/ https://www.ncbi.nlm.nih.gov/pubmed/37301900 http://dx.doi.org/10.1038/s42003-023-04977-x |
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