Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation

Deoxyribozymes (DNAzymes) are in vitro evolved DNA sequences capable of catalyzing chemical reactions. The RNA-cleaving 10-23 DNAzyme was the first DNAzyme to be evolved and possesses clinical and biotechnical applications as a biosensor and a knockdown agent. DNAzymes do not require the recruitment...

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Detalles Bibliográficos
Autores principales: Cramer, Evan R., Starcovic, Sarah A., Avey, Rebekah M., Kaya, Ali I., Robart, Aaron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257704/
https://www.ncbi.nlm.nih.gov/pubmed/37301907
http://dx.doi.org/10.1038/s42004-023-00924-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257704/
https://www.ncbi.nlm.nih.gov/pubmed/37301907
http://dx.doi.org/10.1038/s42004-023-00924-3

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