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Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation
Deoxyribozymes (DNAzymes) are in vitro evolved DNA sequences capable of catalyzing chemical reactions. The RNA-cleaving 10-23 DNAzyme was the first DNAzyme to be evolved and possesses clinical and biotechnical applications as a biosensor and a knockdown agent. DNAzymes do not require the recruitment...
Autores principales: | Cramer, Evan R., Starcovic, Sarah A., Avey, Rebekah M., Kaya, Ali I., Robart, Aaron R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257704/ https://www.ncbi.nlm.nih.gov/pubmed/37301907 http://dx.doi.org/10.1038/s42004-023-00924-3 |
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