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Downregulation of Claudin5 promotes malignant progression and radioresistance through Beclin1-mediated autophagy in esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a highly prevalent and aggressive cancer with poor treatment outcomes. Despite the critical role of tight junction proteins in tumorigenesis, the involvement of Claudin5 in ESCC remains poorly understood. Thus, this study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Huang, Shan, Zhang, Jiayi, Li, Yi, Xu, Yaqiong, Jia, Hui, An, Lei, Wang, Xiaotan, Yang, Yuting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257837/
https://www.ncbi.nlm.nih.gov/pubmed/37303041
http://dx.doi.org/10.1186/s12967-023-04248-7