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DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer

BACKGROUND: DNA methylation changes, frequent early events in cancer, can modulate the binding of transcription factors. RE1-silencing transcription factor (REST) plays a fundamental role in regulating the expression of neuronal genes, and in particular their silencing in non-neuronal tissues, by in...

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Detalles Bibliográficos
Autores principales: Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Zavattari, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257853/
https://www.ncbi.nlm.nih.gov/pubmed/37301955
http://dx.doi.org/10.1186/s13148-023-01514-9