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Metformin inhibits ovarian granular cell pyroptosis through the miR-670-3p/NOX2/ROS pathway

Recent studies have demonstrated that ovarian granular cells (OGCs) pyroptosis is present in the ovaries of polycystic ovary syndrome (PCOS) mice and that NLRP3 activation destroys follicular functions. Metformin has been shown to protect against PCOS by reducing insulin resistance in women, whereas...

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Detalles Bibliográficos
Autores principales: Zhou, Li-Hua, Zou, Hui, Hao, Jia-Yuan, Huang, Yong, Zhang, Jia-Nan, Xu, Xiao-Hong, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258021/
https://www.ncbi.nlm.nih.gov/pubmed/37244286
http://dx.doi.org/10.18632/aging.204745