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Metformin inhibits ovarian granular cell pyroptosis through the miR-670-3p/NOX2/ROS pathway
Recent studies have demonstrated that ovarian granular cells (OGCs) pyroptosis is present in the ovaries of polycystic ovary syndrome (PCOS) mice and that NLRP3 activation destroys follicular functions. Metformin has been shown to protect against PCOS by reducing insulin resistance in women, whereas...
Autores principales: | Zhou, Li-Hua, Zou, Hui, Hao, Jia-Yuan, Huang, Yong, Zhang, Jia-Nan, Xu, Xiao-Hong, Li, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258021/ https://www.ncbi.nlm.nih.gov/pubmed/37244286 http://dx.doi.org/10.18632/aging.204745 |
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