Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex

Cellular senescence is a dynamic stress response process that contributes to aging. From initiation to maintenance, senescent cells continuously undergo complex molecular changes and develop an altered transcriptome. Understanding how the molecular architecture of these cells evolve to sustain their...

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Detalles Bibliográficos
Autores principales: Kandhaya-Pillai, Renuka, Miro-Mur, Francesc, Alijotas-Reig, Jaume, Tchkonia, Tamar, Schwartz, Simo, Kirkland, James L., Oshima, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258023/
https://www.ncbi.nlm.nih.gov/pubmed/37219418
http://dx.doi.org/10.18632/aging.204743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258023/
https://www.ncbi.nlm.nih.gov/pubmed/37219418
http://dx.doi.org/10.18632/aging.204743

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