PCSK6 mediates Th1 differentiation and promotes chronic colitis progression and mucosal barrier injury via STAT1

This study was aimed at investigating the expression and role of proprotein convertase subtilisin/kexin type (PCSK6) in inflammatory bowel disease (IBD). DSS induced mouse colitis and mucosal barrier injury, down-regulation of TJ proteins, improvement of permeability, and increases of the proportion...

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Detalles Bibliográficos
Autores principales: Mei, Xiaoping, Zhou, Hongkun, Song, Zhengwei, Yang, Xiaodan, Liu, Xiaorong, Fei, Jianguo, Shen, Yiyu, Wang, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258034/
https://www.ncbi.nlm.nih.gov/pubmed/37211384
http://dx.doi.org/10.18632/aging.204739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258034/
https://www.ncbi.nlm.nih.gov/pubmed/37211384
http://dx.doi.org/10.18632/aging.204739

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