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Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH

Background: This study aimed to investigate the pathogenic factors of glucocorticoids (GCs)-induced osteonecrosis of the femoral head (GONFH) and its underlying pathogenesis in vivo and in vitro. Methods: Radiographical (µCT) scanning, histopathological, immunohistochemical, reactive oxygen species...

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Detalles Bibliográficos
Autores principales: Xu, Huihui, Zeng, Qinghe, Zou, Kaiao, Huang, Haipeng, Chen, Jiali, Wang, Pinger, Yuan, Wenhua, Xiao, Luwei, Tong, Peijian, Jin, Hongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258081/
https://www.ncbi.nlm.nih.gov/pubmed/37306805
http://dx.doi.org/10.1007/s10495-023-01860-2