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Investigating non-inferiority or equivalence in time-to-event data under non-proportional hazards

The classical approach to analyze time-to-event data, e.g. in clinical trials, is to fit Kaplan–Meier curves yielding the treatment effect as the hazard ratio between treatment groups. Afterwards, a log-rank test is commonly performed to investigate whether there is a difference in survival or, depe...

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Detalles Bibliográficos
Autores principales: Möllenhoff, Kathrin, Tresch, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258187/
https://www.ncbi.nlm.nih.gov/pubmed/36708450
http://dx.doi.org/10.1007/s10985-023-09589-5