RRx-001: a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist

RRx-001 is a shape shifting small molecule with Fast Track designation for the prevention/amelioration of chemoradiation-induced severe oral mucositis (SOM) in newly diagnosed Head and Neck cancer. It has been intentionally developed or “engineered” as a chimeric single molecular entity that targets...

Descripción completa

Detalles Bibliográficos
Autores principales: Oronsky, Bryan, Takahashi, Lori, Gordon, Richard, Cabrales, Pedro, Caroen, Scott, Reid, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258348/
https://www.ncbi.nlm.nih.gov/pubmed/37313460
http://dx.doi.org/10.3389/fonc.2023.1204143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258348/
https://www.ncbi.nlm.nih.gov/pubmed/37313460
http://dx.doi.org/10.3389/fonc.2023.1204143

Ejemplares similares