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RRx-001: a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist

RRx-001 is a shape shifting small molecule with Fast Track designation for the prevention/amelioration of chemoradiation-induced severe oral mucositis (SOM) in newly diagnosed Head and Neck cancer. It has been intentionally developed or “engineered” as a chimeric single molecular entity that targets...

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Detalles Bibliográficos
Autores principales:	Oronsky, Bryan, Takahashi, Lori, Gordon, Richard, Cabrales, Pedro, Caroen, Scott, Reid, Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258348/ https://www.ncbi.nlm.nih.gov/pubmed/37313460 http://dx.doi.org/10.3389/fonc.2023.1204143

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