Cargando…

Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity

The aberrant activation of Wnt/β-catenin signaling in tumor cells and immune cells in the tumor microenvironment (TME) promotes malignant transformation, metastasis, immune evasion, and resistance to cancer treatments. The increased Wnt ligand expression in TME activates β-catenin signaling in antig...

Descripción completa

Detalles Bibliográficos
Autores principales: Pundkar, Chetan, Antony, Ferrin, Kang, Xuejia, Mishra, Amarjit, Babu, R. Jayachandra, Chen, Pengyu, Li, Feng, Suryawanshi, Amol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258387/
https://www.ncbi.nlm.nih.gov/pubmed/37313143
http://dx.doi.org/10.1016/j.heliyon.2023.e16688