Changes in the expression of cancer- and metastasis-related genes and proteins after metformin treatment under different metabolic conditions in endometrial cancer cells

RESEARCH QUESTION: Hyperinsulinemia and elevated estrogen levels are known risk factors for endometrial cancer (EC) development and are associated with obesity, type 2 diabetes mellitus (T2DM), insulin resistance, among others. Metformin, an insulin-sensitizing drug, displays anti-tumor effects in c...

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Detalles Bibliográficos
Autores principales: Lange, Carsten, Brüggemann, Jana, Thüner, Theresa, Jauckus, Julia, Strowitzki, Thomas, Germeyer, Ariane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258389/
https://www.ncbi.nlm.nih.gov/pubmed/37313172
http://dx.doi.org/10.1016/j.heliyon.2023.e16678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258389/
https://www.ncbi.nlm.nih.gov/pubmed/37313172
http://dx.doi.org/10.1016/j.heliyon.2023.e16678

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