Cargando…

Suboptimal Mitochondrial Activity Facilitates Nuclear Heat Shock Responses for Proteostasis and Genome Stability

Thermal stress induces dynamic changes in nuclear proteins and relevant physiology as a part of the heat shock response (HSR). However, how the nuclear HSR is fine-tuned for cellular homeostasis remains elusive. Here, we show that mitochondrial activity plays an important role in nuclear proteostasi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Dongkeun, Yu, Youngim, Kim, Ji-hyung, Lee, Jongbin, Park, Jongmin, Hong, Kido, Seo, Jeong-Kon, Lim, Chunghun, Min, Kyung-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258458/ https://www.ncbi.nlm.nih.gov/pubmed/37077029 http://dx.doi.org/10.14348/molcells.2023.2181

Ejemplares similares

The trinity of ribosome-associated quality control and stress signaling for proteostasis and neuronal physiology
por: Park, Jumin, et al.
Publicado: (2021)

Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges
por: Alagar Boopathy, Lokha R., et al.
Publicado: (2022)

mtIF3 is locally translated in axons and regulates mitochondrial translation for axonal growth
por: Lee, Soyeon, et al.
Publicado: (2022)

Insights and Perspectives on the Role of Proteostasis and Heat Shock Proteins in Fungal Infections
por: Neves-da-Rocha, João, et al.
Publicado: (2023)

ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD
por: Park, Jumin, et al.
Publicado: (2021)

Metabolic flux from the Krebs cycle to glutamate transmission tunes a neural brake on seizure onset
por: Jeong, Jiwon, et al.
Publicado: (2021)

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock
por: Liebelt, Frauke, et al.
Publicado: (2019)

Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation
por: Shinkawa, Toyohide, et al.
Publicado: (2011)

Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation
por: Espinoza, Mateo F., et al.
Publicado: (2022)

Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance
por: Franić, Dina, et al.
Publicado: (2021)

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome
por: Liang, Vanessa, et al.
Publicado: (2014)

Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells
por: Boridy, S, et al.
Publicado: (2014)

LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival
por: Lee, Yu Geon, et al.
Publicado: (2021)

The 70-kD heat shock cognate protein (hsc70) facilitates the nuclear export of the import receptors
por: Kose, Shingo, et al.
Publicado: (2005)

Drosophila CrebB is a Substrate of the Nonsense-Mediated mRNA Decay Pathway that Sustains Circadian Behaviors
por: Ri, Hwajung, et al.
Publicado: (2019)

Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control
por: Samant, Rahul S., et al.
Publicado: (2018)

Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis
por: Dion, William, et al.
Publicado: (2022)

Heat Shock Proteins: A Review of the Molecular Chaperones for Plant Immunity
por: Park, Chang-Jin, et al.
Publicado: (2015)

The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein
por: Shi, Chao, et al.
Publicado: (2015)

Multi-Level Interactions Between Heat Shock Factors, Heat Shock Proteins, and the Redox System Regulate Acclimation to Heat
por: Driedonks, Nicky, et al.
Publicado: (2015)

twenty-four defines a critical translational step in the Drosophila clock
por: Lim, Chunghun, et al.
Publicado: (2011)

A sleep-like state in Hydra unravels conserved sleep mechanisms during the evolutionary development of the central nervous system
por: Kanaya, Hiroyuki J., et al.
Publicado: (2020)

Techniques for investigating mitochondrial gene expression
por: Park, Dongkeun, et al.
Publicado: (2020)

Alteration by heat shock and immunological characterization of Drosophila small nuclear ribonucleoproteins
Publicado: (1989)

Serine metabolism in the brain regulates starvation-induced sleep suppression in Drosophila melanogaster
por: Sonn, Jun Young, et al.
Publicado: (2018)

Accumulation, stability, and localization of a major chloroplast heat- shock protein
Publicado: (1990)

OLA1 protects cells in heat shock by stabilizing HSP70
por: Mao, R-F, et al.
Publicado: (2013)

Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans
por: Kumsta, Caroline, et al.
Publicado: (2017)

Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors
por: Fu, Yan-Lin, et al.
Publicado: (2018)

Longevity and GAPDH Stability in Bivalves and Mammals: A Convenient Marker for Comparative Gerontology and Proteostasis
por: Treaster, Stephen B., et al.
Publicado: (2015)

Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy
por: Sin, Yuan Yan, et al.
Publicado: (2015)

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity
por: Jang, Jihoon, et al.
Publicado: (2018)

Heat Shock Protein 90 in Alzheimer's Disease
por: Ou, Jiang-Rong, et al.
Publicado: (2014)

Proteostasis in pediatric pulmonary pathology
por: Meiners, Silke, et al.
Publicado: (2014)

Protein Folding and Mechanisms of Proteostasis
por: Díaz-Villanueva, José Fernando, et al.
Publicado: (2015)

Proteostasis and Diseases of the Motor Unit
por: Rinaldi, Carlo, et al.
Publicado: (2016)

Epigenetic inheritance of proteostasis and ageing
por: Li, Cheryl, et al.
Publicado: (2016)

CHIPped balance of proteostasis and longevity
por: Pokrzywa, Wojciech, et al.
Publicado: (2017)

The Contribution of the 20S Proteasome to Proteostasis
por: Kumar Deshmukh, Fanindra, et al.
Publicado: (2019)

Proteostasis During Cerebral Ischemia
por: Thiebaut, Audrey M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fetlf0kdbd93ftib3nb2vrr1rj