Targeting KAT2A inhibits inflammatory macrophage activation and rheumatoid arthritis through epigenetic and metabolic reprogramming

Epigenetic regulation of inflammatory macrophages governs inflammation initiation and resolution in the pathogenesis of rheumatoid arthritis (RA). Nevertheless, the mechanisms underlying macrophage‐mediated arthritis injuries remain largely obscure. Here, we found that increased expression of lysine...

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Detalles Bibliográficos
Autores principales: Zhang, Yunkai, Gao, Ying, Ding, Yingying, Jiang, Yuyu, Chen, Huiying, Zhan, Zhenzhen, Liu, Xingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258526/
https://www.ncbi.nlm.nih.gov/pubmed/37313329
http://dx.doi.org/10.1002/mco2.306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258526/
https://www.ncbi.nlm.nih.gov/pubmed/37313329
http://dx.doi.org/10.1002/mco2.306

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