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A self‐propagating, barcoded transposon system for the dynamic rewiring of genomic networks

In bacteria, natural transposon mobilization can drive adaptive genomic rearrangements. Here, we build on this capability and develop an inducible, self‐propagating transposon platform for continuous genome‐wide mutagenesis and the dynamic rewiring of gene networks in bacteria. We first use the plat...

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Detalles Bibliográficos
Autores principales: English, Max A, Alcantar, Miguel A, Collins, James J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258560/
https://www.ncbi.nlm.nih.gov/pubmed/36970845
http://dx.doi.org/10.15252/msb.202211398