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GRaNIE and GRaNPA: inference and evaluation of enhancer‐mediated gene regulatory networks

Enhancers play a vital role in gene regulation and are critical in mediating the impact of noncoding genetic variants associated with complex traits. Enhancer activity is a cell‐type‐specific process regulated by transcription factors (TFs), epigenetic mechanisms and genetic variants. Despite the st...

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Detalles Bibliográficos
Autores principales: Kamal, Aryan, Arnold, Christian, Claringbould, Annique, Moussa, Rim, Servaas, Nila H, Kholmatov, Maksim, Daga, Neha, Nogina, Daria, Mueller‐Dott, Sophia, Reyes‐Palomares, Armando, Palla, Giovanni, Sigalova, Olga, Bunina, Daria, Pabst, Caroline, Zaugg, Judith B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258561/
https://www.ncbi.nlm.nih.gov/pubmed/37073532
http://dx.doi.org/10.15252/msb.202311627