Predicting cellular responses to complex perturbations in high‐throughput screens

Recent advances in multiplexed single‐cell transcriptomics experiments facilitate the high‐throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally unfeasible. Therefore, computational methods are needed to predi...

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Detalles Bibliográficos
Autores principales: Lotfollahi, Mohammad, Klimovskaia Susmelj, Anna, De Donno, Carlo, Hetzel, Leon, Ji, Yuge, Ibarra, Ignacio L, Srivatsan, Sanjay R, Naghipourfar, Mohsen, Daza, Riza M, Martin, Beth, Shendure, Jay, McFaline‐Figueroa, Jose L, Boyeau, Pierre, Wolf, F Alexander, Yakubova, Nafissa, Günnemann, Stephan, Trapnell, Cole, Lopez‐Paz, David, Theis, Fabian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258562/
https://www.ncbi.nlm.nih.gov/pubmed/37154091
http://dx.doi.org/10.15252/msb.202211517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258562/
https://www.ncbi.nlm.nih.gov/pubmed/37154091
http://dx.doi.org/10.15252/msb.202211517

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