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Unraveling the glycosylated immunopeptidome with HLA-Glyco

Recent interest in targeted therapies has been sparked by the study of MHC-associated peptides (MAPs) that undergo post-translational modifications (PTMs), particularly glycosylation. In this study, we introduce a fast computational workflow that merges the MSFragger-Glyco search algorithm with a fa...

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Detalles Bibliográficos
Autores principales: Bedran, Georges, Polasky, Daniel A., Hsiao, Yi, Yu, Fengchao, da Veiga Leprevost, Felipe, Alfaro, Javier A., Cieslik, Marcin, Nesvizhskii, Alexey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258777/
https://www.ncbi.nlm.nih.gov/pubmed/37308510
http://dx.doi.org/10.1038/s41467-023-39270-2