Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson’s Disease

[Image: see text] Prolyl oligopeptidase (PREP) is a widely distributed serine protease in the human body cleaving proline-containing peptides; however, recent studies suggest that its effects on pathogenic processes underlying neurodegeneration are derived from direct protein–protein interactions (P...

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Detalles Bibliográficos
Autores principales: Kilpeläinen, Tommi P., Pätsi, Henri T., Svarcbahs, Reinis, Julku, Ulrika H., Eteläinen, Tony S., Cui, Hengjing, Auno, Samuli, Sipari, Nina, Norrbacka, Susanna, Leino, Teppo O., Jäntti, Maria, Myöhänen, Timo T., Wallén, Erik A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258805/
https://www.ncbi.nlm.nih.gov/pubmed/37248563
http://dx.doi.org/10.1021/acs.jmedchem.3c00235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258805/
https://www.ncbi.nlm.nih.gov/pubmed/37248563
http://dx.doi.org/10.1021/acs.jmedchem.3c00235

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