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HNRNPA2B1-mediated m(6)A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis
BACKGROUND: Accumulating data indicate that N6-methyladenosine (m(6)A) RNA methylation and lncRNA deregulation act crucial roles in cancer progression. Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) as an m(6)A “reader” has been reported to be an oncogene in multiple malignancies. We herei...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258935/ https://www.ncbi.nlm.nih.gov/pubmed/37308993 http://dx.doi.org/10.1186/s12967-023-04190-8 |