HNRNPA2B1-mediated m(6)A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis

BACKGROUND: Accumulating data indicate that N6-methyladenosine (m(6)A) RNA methylation and lncRNA deregulation act crucial roles in cancer progression. Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) as an m(6)A “reader” has been reported to be an oncogene in multiple malignancies. We herei...

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Detalles Bibliográficos
Autores principales: Li, Ke, Gong, Quan, Xiang, Xu-Dong, Guo, Gang, Liu, Jia, Zhao, Li, Li, Jun, Chen, Nan, Li, Heng, Zhang, Li-Juan, Zhou, Chun-Yan, Wang, Zhi-Yong, Zhuang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258935/
https://www.ncbi.nlm.nih.gov/pubmed/37308993
http://dx.doi.org/10.1186/s12967-023-04190-8

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