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Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

BACKGROUND: Ferroptosis, a unique form of non-apoptotic cell death, is dependent on iron and lipoperoxidation, and has been shown to be associated with the pathogenesis of inflammatory bowel disease (IBD). Human umbilical cord mesenchymal stem cell-derived exosomes (hucMSC-Ex) are involved in cell s...

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Detalles Bibliográficos
Autores principales: Wei, Zhiping, Hang, Sanhua, Wiredu Ocansey, Dickson Kofi, Zhang, Zhaoyang, Wang, Bo, Zhang, Xu, Mao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259042/
https://www.ncbi.nlm.nih.gov/pubmed/37303049
http://dx.doi.org/10.1186/s12951-023-01951-x