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Myofibroblast senescence promotes arrhythmogenic remodeling in the aged infarcted rabbit heart

Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and accelerate age-associated diseases. Senescent cells in...

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Detalles Bibliográficos
Autores principales: Baggett, Brett C, Murphy, Kevin R, Sengun, Elif, Mi, Eric, Cao, Yueming, Turan, Nilufer N, Lu, Yichun, Schofield, Lorraine, Kim, Tae Yun, Kabakov, Anatoli Y, Bronk, Peter, Qu, Zhilin, Camelliti, Patrizia, Dubielecka, Patrycja, Terentyev, Dmitry, del Monte, Federica, Choi, Bum-Rak, Sedivy, John, Koren, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259375/
https://www.ncbi.nlm.nih.gov/pubmed/37204302
http://dx.doi.org/10.7554/eLife.84088