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The impact of single nucleotide polymorphisms in MTHFR and MTRR genes on disease activity and the presence of methotrexate treatment side effects in children with juvenile idiopathic arthritis

INTRODUCTION: To determine the impact of single nucleotide polymorphisms (SNPs) in MTHFR and MTRR genes on disease activity and the presence of MTX therapy adverse events in Polish children with juvenile idiopathic arthritis (JIA). METHODS: SNP genotyping was performed using genomic DNA isolated fro...

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Detalles Bibliográficos
Autores principales: Roszkiewicz, Justyna, Michałek, Dominika, Ryk, Aleksandra, Szmyd, Bartosz, Smolewska, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259383/
https://www.ncbi.nlm.nih.gov/pubmed/37313208
http://dx.doi.org/10.5114/aoms/163259