The structural basis of the multi-step allosteric activation of Aurora B kinase

Aurora B, together with IN-box, the C-terminal part of INCENP, forms an enzymatic complex that ensures faithful cell division. The [Aurora B/IN-box] complex is activated by autophosphorylation in the Aurora B activation loop and in IN-box, but it is not clear how these phosphorylations activate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Segura-Peña, Dario, Hovet, Oda, Gogoi, Hemanga, Dawicki-McKenna, Jennine, Hansen Wøien, Stine Malene, Carrer, Manuel, Black, Ben E, Cascella, Michele, Sekulic, Nikolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259393/
https://www.ncbi.nlm.nih.gov/pubmed/37227118
http://dx.doi.org/10.7554/eLife.85328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259393/
https://www.ncbi.nlm.nih.gov/pubmed/37227118
http://dx.doi.org/10.7554/eLife.85328

Ejemplares similares