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The structural basis of the multi-step allosteric activation of Aurora B kinase

Aurora B, together with IN-box, the C-terminal part of INCENP, forms an enzymatic complex that ensures faithful cell division. The [Aurora B/IN-box] complex is activated by autophosphorylation in the Aurora B activation loop and in IN-box, but it is not clear how these phosphorylations activate the...

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Detalles Bibliográficos
Autores principales:	Segura-Peña, Dario, Hovet, Oda, Gogoi, Hemanga, Dawicki-McKenna, Jennine, Hansen Wøien, Stine Malene, Carrer, Manuel, Black, Ben E, Cascella, Michele, Sekulic, Nikolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259393/ https://www.ncbi.nlm.nih.gov/pubmed/37227118 http://dx.doi.org/10.7554/eLife.85328

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