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The large GTPase Sey1/atlastin mediates lipid droplet- and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila

The amoeba-resistant bacterium Legionella pneumophila causes Legionnaires’ disease and employs a type IV secretion system (T4SS) to replicate in the unique, ER-associated Legionella-containing vacuole (LCV). The large fusion GTPase Sey1/atlastin is implicated in ER dynamics, ER-derived lipid droplet...

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Detalles Bibliográficos
Autores principales: Hüsler, Dario, Stauffer, Pia, Keller, Bernhard, Böck, Desirée, Steiner, Thomas, Ostrzinski, Anne, Vormittag, Simone, Striednig, Bianca, Swart, A Leoni, Letourneur, François, Maaß, Sandra, Becher, Dörte, Eisenreich, Wolfgang, Pilhofer, Martin, Hilbi, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259473/
https://www.ncbi.nlm.nih.gov/pubmed/37158597
http://dx.doi.org/10.7554/eLife.85142