Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain

Prolonged exposure to loud noise has been shown to affect inner ear sensory hair cells in a variety of deleterious manners, including damaging the stereocilia core. The damaged sites can be visualized as ‘gaps’ in phalloidin staining of F-actin, and the enrichment of monomeric actin at these sites,...

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Detalles Bibliográficos
Autores principales: Wagner, Elizabeth L, Im, Jun-Sub, Sala, Stefano, Nakahata, Maura I, Imbery, Terence E, Li, Sihan, Chen, Daniel, Nimchuk, Katherine, Noy, Yael, Archer, David W, Xu, Wenhao, Hashisaki, George, Avraham, Karen B, Oakes, Patrick W, Shin, Jung-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259482/
https://www.ncbi.nlm.nih.gov/pubmed/37294664
http://dx.doi.org/10.7554/eLife.72681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259482/
https://www.ncbi.nlm.nih.gov/pubmed/37294664
http://dx.doi.org/10.7554/eLife.72681

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