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Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain
Prolonged exposure to loud noise has been shown to affect inner ear sensory hair cells in a variety of deleterious manners, including damaging the stereocilia core. The damaged sites can be visualized as ‘gaps’ in phalloidin staining of F-actin, and the enrichment of monomeric actin at these sites,...
Autores principales: | Wagner, Elizabeth L, Im, Jun-Sub, Sala, Stefano, Nakahata, Maura I, Imbery, Terence E, Li, Sihan, Chen, Daniel, Nimchuk, Katherine, Noy, Yael, Archer, David W, Xu, Wenhao, Hashisaki, George, Avraham, Karen B, Oakes, Patrick W, Shin, Jung-Bum |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259482/ https://www.ncbi.nlm.nih.gov/pubmed/37294664 http://dx.doi.org/10.7554/eLife.72681 |
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