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RNF112-mediated FOXM1 ubiquitination suppresses the proliferation and invasion of gastric cancer

Forkhead box M1 (FOXM1) plays a critical role in development physiologically and tumorigenesis pathologically. However, insufficient efforts have been dedicated to exploring the regulation, in particular the degradation of FOXM1. Here, the ON-TARGETplus siRNA library targeting E3 ligases was used to...

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Detalles Bibliográficos
Autores principales: Zhang, Shengwei, Wang, Jing, Hu, Weichao, He, Lijiao, Tang, Qingyun, Li, Jie, Jie, Mengmeng, Li, Xinzhe, Liu, Cheng, Ouyang, Qin, Yang, Shiming, Hu, Changjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259508/
https://www.ncbi.nlm.nih.gov/pubmed/37288663
http://dx.doi.org/10.1172/jci.insight.166698