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Dysfunction of programmed embryo senescence is linked to genetic developmental defects

Developmental senescence is a form of programmed senescence that contributes to morphogenesis during embryonic development. We showed recently that the SIX1 homeoprotein, an essential regulator of organogenesis, is also a repressor of adult cellular senescence. Alterations in the SIX/EYA pathway are...

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Detalles Bibliográficos
Autores principales: de Lope, Cristina, García-Lucena, Rebeca, Magariños, Marta, León, Yolanda, Casa-Rodríguez, Nuria, Contreras, Nuria, Escudero-Iriarte, Carmen, Varela-Nieto, Isabel, Maire, Pascal, Palmero, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259514/
https://www.ncbi.nlm.nih.gov/pubmed/37017267
http://dx.doi.org/10.1242/dev.200903